HFC-134a is used as refrigerant in automobile air-conditioning, household and commercial refrigerant applications. It can also be used as aerosol, flame retardan, and blowing agent in pharmaceutical, agro-chemical, cosmetics and cleaning sectors.

R404A is formulated to closely match the properties of Refrigerant R502, making it useful for a variety of medium and low temperature refrigeration applications.Refrigerant R404A has been approved by many refrigeration compressor and system manufacturers for use in new refrigeration equipment such as food display and storage cases, cold storage rooms, ice machines, transportation, and process refrigeration.

R410A refrigerant is used in new residential and commercial air conditioning systems, heat pumps, dehumidifiers and small chillers. R-410A is also being considered in some medium temperature refrigeration applications.

Chlorodifluoromethane (HCFC-22), a colorless gas at room temperature, is a colorless, non - toxic, non-flammable and transparent liquid under the pressure created by itself. It has excellent thermal and chemical stabilities and no corrosivity to metals. Its main applications include refrigerant(-80℃grade), raw material for PTFE production and intermediate for Halon 1211 production.

R-408A is a retrofit solution for medium and low temperature refrigeration systems that are currently using R-502. R-408A should not be mixed with R-502 or used to top off the charge of an existing system operating on R-502.

R-406A is a mixture of three components chlorodifluoromethane (R-22), isobutane (R-600a) and chlorodifluoroethane (R-142b) in the ratio 55/4/41. R406A was designed as a replacement for R-12, which is compatible with the typical mineral oil lubricants used in R-12 systems. It has a range of boiling points which may increase the effectiveness of the heat transfer elements in refrigeration equipment. As it contains R-22, its future is limited due to eventual phase-out.

R407C is a mixture of hydrofluorocarbons used as a refrigerant. It is a zeotropic blend of R-32, R-125, and R-134a (20/40/40). Applications include residential and commercial air conditioning systems, non-flooded evaporator chillers, and some commercial refrigeration systems. Since R-407C has similar properties to R-22, it is possible (with modifications) to use it in the same equipment designed for R-22 today.

As the long-term substitute for R502, R507 used mainly in the low temperature refrigeranting systems.